Edie Sedgwick (1943 - 1971)
Cousin of Kyra Sedgwick
Lupe (1966) [Lupe Velez]: Commits suicide by taking an overdose of sleeping pills; she dies after passing out in the bathroom. (This is based more on the popular misconception of Lupe Velez' death than on the actual truth; in reality, Velez' body was found in her bedroom.)

Ciao Manhattan (1972) [Susan Superstar]: Dies (off-screen) of a drug overdose; we learn of her death afterwards when Wesley Hayes sees a newspaper headline about it. (Due to Edie's actual death before the film was completed, a genuine newspaper article was used, with her name obscured so that the filmmakers could apply it to her character.)

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Edie Sedgwick in 'Lupe'