Laurie Metcalf (1955 - )
Ex-Mrs. Jeff Perry
Mrs. Matt Roth
Mother of Zoe Perry
Scream 2 (1997) [Debbie Salt a.k.a. Mrs. Loomis]: Shot in the chest by Liev Schreiber, then shot in the head by Neve Campbell to make sure she's dead.

Desperate Housewives: Bang (2006) [Carolyn Bigsby]: Shot in the head by Kathleen Gati, after Laurie drops her gun during a struggle with Josh Henderson and Kathleen picks up the gun. (Thanks to PortsGuy and Neil)

Raines: Reconstructing Alice (2007) [Alice Brody]: Shot to death by Todd Giebenhain while she's sleeping on the street. Her body is shown at the beginning of the episode while Jeff Goldblum investigates the scene, and the murder is shown in a flashback later on. She also appears as a figment of Jeff's imagination throughout the episode. (Thanks to Neil)
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Laurie Metcalf in 'Scream 2'